Cisplatin hela
WebSep 18, 2024 · National Center for Biotechnology Information WebFeb 1, 2015 · In cell proliferation experiments, HeLa cells were treated with either cisplatin or myricetin and methyl eugenol alone, or vehiclealone for 12, 24 and 48 h. For apoptosis assay, cells weretreated with cisplatin or myricetin and methyl eugenol either alone or combined, or vehicle alone for 48 h.
Cisplatin hela
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WebAug 21, 2024 · Monitoring of the HeLa and HeLa-SypHer2 tumor growth during the 35 days after tumor challenge showed that cisplatin treatment (5 mg/kg, totaling 11 doses over 4 weeks) clearly impeded tumor growth. WebNational Center for Biotechnology Information
WebAug 6, 2024 · Cisplatin is a platinum-based chemotherapeutic agent that is widely used for the treatment of malignant tumors, such as cervical cancer, lung cancer, and ovarian cancer [3]. Cisplatin mainly induces cross-linking at the N7-position of guanosine, which modifies DNA to induce apoptosis and kill cancer cells [4]. WebA cisplatin-resistant cell subline, HeLa/CDDP cells, showed a 19-fold resistance to cisplatin compared with the parent cells. The subline showed a collateral sensitivity to paclitaxel. An equitoxic dose (IC50) of cisplatin produced DNA fragmentation in HeLa …
WebFeb 11, 2024 · Subsequently, cells were treated with IC 50 doses of 5-FU (17.58 μM: SiHa; 15.31 μM: HeLa) and cisplatin (24.14 μM: SiHa; 6.82 μM: HeLa) for 48 h and the exosomes were isolated from the conditioned media of treated cells. The exosomal RNA was isolated and examined for modulation of HPV transcripts by type-specific HPVE6 and E7 RT-PCR. WebOct 28, 2024 · Although the concurrent use of a chemotherapeutic agent and radiotherapy improves survival in patients with locally advanced or recurrent cervical cancer, severe side effects related to chemotherapy are frequent and may result in …
WebJun 1, 2024 · IC90 of paclitaxel in HeLa Pac RB was increased from 69 pM, 440 pM, 2,561 pM and 10,337 pM on 0th, 1st, 2nd, 3rd and 4th months, respectively. Interestingly, the resistant cells were recovered to...
WebFeb 12, 2024 · MBNL1 regulates resistance of HeLa cells to cisplatin via Nrf2 Chemotherapy is an important method in the treatment of cervical cancer, but some patients will face drug resistance, which often indicates a poor prognosis. Moreover, there is no complete solution at present. sharing passwords netflixWebAug 21, 2024 · Effect of cisplatin on the proliferative activity and survival of cancer cells. ( A) Viable cell number for HeLa and HeLa-SypHer2 cells. ( B) Percentage of dead (trypan blue positive) cells.... sharing patient informationWebCisplatin, as a significant chemotherapeutic drug for the treatment of cancers, was combined with rapamycin (RAPA), an autophagy inducer, or 3-methyladenine (3-MA), an autophagy inhibitor, and these cisplatin … poppy toys from poppy playtimeWebApr 13, 2024 · HIGHLIGHTS. who: Florentine S. B. Subtil et al. from the Department of Radiotherapy and Radiooncology, Philipps-University, Marburg, Germany have published the research: Dual PI3K/mTOR Inhibitor NVP-BEZ235 Leads to a Synergistic Enhancement of Cisplatin and Radiation in Both HPV-Negative and -Positive HNSCC Cell Lines, in the … poppy toys youtubeWebFor IFNβ-cisplatin sequential treatment protocol (E), HeLa cells were treated with 100 ng/mL IFNβ for 24, 48, or 72 h, and then cells were replated in 96-well plates and treated … poppy toxicityWebJan 12, 2024 · Cisplatin-resistant HeLa cells were transfected with NHERF1 and overexpression of NHERF1 protein was confirmed by Western blotting ( Figure 2 A). Effect of NHERF1 on cell growth was examined by CCK8 … sharing pc game passWebCisplatin is a platinum chemotherapeutic used in a variety of malignancies. The antineoplastic activity occurs from DNA cross-links and adducts, in addition to the generation of superoxide radicals. Nephrotoxicity is the most well-known and potentially most clinically significant toxicity. poppy trading