WebNov 1, 2014 · Pre-existing immunity against human adenovirus (HAd) serotype 5 derived vector in the human population is widespread, thus hampering its clinical use. Various components of the immune system, including neutralizing antibodies (nAbs), Ad specific T cells and type I IFN activated NK cells, contribute to dampening the efficacy of Ad … Web57. 2013. Characterization of a monoclonal antibody as the first specific inhibitor of human NTP diphosphohydrolase‐3: partial characterization of the inhibitory epitope and potential …
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